ATP11B基因編碼功能及結(jié)構(gòu)描述
P型atp酶，如atpp11b，在其中間狀態(tài)被磷酸化，并推動(dòng)離子在膜上的上坡轉(zhuǎn)運(yùn)已鑒定出P型atp酶的幾個(gè)亞家族一個(gè)亞科運(yùn)輸重金屬離子，如cu（2+）、cd（2+）。另一個(gè)亞科運(yùn)輸非重金屬離子，如H+、Na+、K+、或Ca+。第三個(gè)亞科運(yùn)輸兩棲動(dòng)物，如磷脂酰絲氨酸。
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
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